The Breast Oncology laboratory is seeking post-doctoral candidates to investigate in a preclinical triple-negative breast cancer models potential experimental therapeutics including immune-related approaches. The studies address in a multi-disciplinary approach the mechanistic questions arising from the use of immunotherapies either as single agents or in different molecular targeted drug combinations directed to modify the tumor microenvironment. In addition to in vitro and in vivo experimental models, we use samples collected from currently ongoing clinical trials where novel therapies are being tested. Multi-disciplinary approaches are applied as our laboratory has existing collaborations with research and clinical groups at NCI and Universities, as well as at the Houston Methodist Research institute, where the Breast Oncology laboratory is located. Salaries are commensurate and based in the experience of the candidates and are managed by the department of Human Resources of the HMRI as per existing labor-related laws including health insurance and other benefits. Candidates should submit their CV and information on 3 references that may be contacted to: rrrosato@houstonmethodist.org; jfmontier@houstonmethodist.org
